Acetate Buffer, 0.2M, pH3.5-5.6

1. Identification

Product Identifiers

Product Name

Acetate Buffer, 0.2M, pH3.5-5.6

Other Names

Acetate Buffer, 0.2M, pH3.6

Product Number(s)

11480, 11482, EMS11480, EMS11482

CAS Number

Not available.

Recommended use of the chemical and restriction on use

Company Details

Emergency Contact Details

2. Hazards Identification

Classification of the substance or mixture

Label Elements

Signal Words

None

Hazard Statement(s)

• Hazard-determining components of labelling:
• SODIIUM ACETATE TRIHYDRATE
• Acetic Acid Glacial
• Flammable liquid and vapour.
• Fatal if swallowed, in contact with skin or if inhaled.
• Causes severe skin burns and eye damage.

Precautionary Statement(s)

• Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• Ground / bond container and receiving equipment.
• Use explosion-proof [electrical/ventilating/lighting] equipment.
• Use non-sparking tools.
• Take action to prevent static discharge.
• Do not breathe dusts or mists.
• Do not get in eyes, on skin, or on clothing.
• Wash thoroughly after handling.
• Do not eat, drink or smoke when using this product.
• Use only outdoors or in a well-ventilated area.
• Wear protective gloves/protective clothing/eye protection/face protection/hearing protection.
• [In case of inadequate ventilation] wear respiratory protection.

Primary route(s) of entry

Human Health

Inhalation

Remove victim to fresh air and keep at rest in a position comfortable for breathing.

Ingestion

Immediately call a POISON CENTER/doctor. Rinse mouth. Do NOT induce vomiting.

Eyes

Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Skin

(or hair) Remove/take off immediately all contaminated clothing. Rinse skin with water/shower. Take off immediately all contaminated clothing and wash it before reuse.

Environment

3. Composition / Information on Ingredients

4. First Aid Measures

Ingestion

• Do not induce vomiting; call for medical help immediately.
• Drink plenty of water and provide fresh air. Call for a doctor immediately.

Inhalation

• Supply fresh air or oxygen; call for a doctor.
• In case of unconsciousness place patient stably in side position for transportation.

Skin Contact

immediately wash with water and soap and rinse thoroughly.

Eye Contact

Rinse opened eye for several minutes under running water. Then consult a doctor.

Other Information

• Immediately remove any clothing soiled by the product.
• Remove breathing equipment only after contaminated clothing have been completely removed.
• In case of irregular breathing or respiratory arrest provide artificial respiration.

5. Firefighting Measures

Suitable extinguishing equipment

Fire

CO₂, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

HAZCHEM

No further relevant information available.

Special protective equipment and precautions for fire fighters

6. Accidental Release Measures

Personal precautions, protective equipment and emergency procedures

• Wear protective equipment. Keep unprotected persons away.
• Protective Action Criteria for Chemicals
• PAC-1:
• 64-19-7 Acetic Acid Glacial 5 ppm
• 6131-90-4 SODIUM ACETATE TRIHYDRATE 11 mg/m³
• PAC-2:
• 64-19-7 Acetic Acid Glacial 35 ppm
• 6131-90-4 SODIUM ACETATE TRIHYDRATE 120 mg/m³
• PAC-3:
• 64-19-7 Acetic Acid Glacial 250 ppm
• 6131-90-4 SODIUM ACETATE TRIHYDRATE 690 mg/m³

Environmental precautions

• Dilute with plenty of water.
• Do not allow to enter sewers/surface or ground water.

Methods and materials for containment and clean up

• Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
• Use neutralising agent.
• Dispose contaminated material as waste according to item 13.
• Ensure adequate ventilation.

7. Handling and Storage

Precautions for safe handling

• Ensure good ventilation/exhaustion at the workplace.
• Open and handle receptacle with care.
• Prevent formation of aerosols.
• Keep ignition sources away - Do not smoke.
• Protect from heat.
• Protect against electrostatic charges.
• Keep respiratory protective device available.

Conditions for safe storage

• Keep container tightly sealed.
• Protect from heat and direct sunlight.

8. Exposure Controls / Personal Protection

Exposure Standards

Engineering controls

• Keep away from foodstuffs, beverages and feed.
• Immediately remove all soiled and contaminated clothing.
• Wash hands before breaks and at the end of work.
• Store protective clothing separately.
• Avoid contact with the eyes.
• Avoid contact with the eyes and skin.

Personal protective equipment

Eye and face protection

Tightly sealed goggles.

Skin protection

• Protective gloves
• The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
• Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
• Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
• Material of gloves
• The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of
• the glove material can not be calculated in advance and has therefore to be checked prior to the application.
• Penetration time of glove material
• The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

Body protection

Wear protective clothing.

Respiratory protection

In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use self-contained respiratory protective device.

9. Physical and Chemical Properties

General information

Appearance

Clear liquid

Odour

Pungent

pH

5.2 at 20°C

Vapour Pressure

11.4hPa at 20°C

Density

Not determined.

Boiling Point

100 °C (212 °F)

Melting Point

Undetermined

Solubility

Fully miscible.

Specific Gravity of Density

Not available.

Flash Point

43°C

Flammable (Explosive) Limits

• Lower: 4 Vol%
• Upper: 19.9 Vol%

Ignition Temperature

427 °C (800.6 °F)

Formula

Not available.

10. Stability and Reactivity

Reactivity

No further relevant information available.

Chemical stability

No decomposition if used according to specifications.

Possibility of hazardous reactions

No dangerous reactions known.

Conditions to avoid

No further relevant information available.

Incompatible materials

No further relevant information available.

11. Toxicological Information

Acute effects

• Acetic Acid Glacial
• Oral LD50 3310 mg/kg (rat)
• Dermal LD50 1060 mg/kg (rabbit)

Eye contact

• Strong caustic effect.
• Strong irritant with the danger of severe eye injury.

Skin contact

Strong caustic effect on skin and mucous membranes.

Ingestion

Swallowing will lead to a strong caustic effect on mouth and throat and to the danger of perforation of oesophagus and stomach.

Inhalation

No sensitising effects known.

Toxicity and irritation

• The product shows the following dangers according to internally approved calculation methods for preparations:
• Corrosive
• Irritant
• Very toxic
• Danger through skin absorption.
• Swallowing will lead to a strong caustic effect on mouth and throat and to the danger of perforation of esophagus
• and stomach.
• Interactive effects No interactive effects between components are known.
• Carcinogenic categories
• IARC (International Agency for Research on Cancer): None of the ingredients is listed.
• NTP (National Toxicology Program): None of the ingredients is listed.
• OSHA-Ca (Occupational Safety Health Administration): None of the ingredients is listed.
• Alternative sources for toxicological information
• No non-standard sources for toxicological information where used.

12. Ecological Information

Ecotoxicity

No further relevant information available.

Persistence and degradability

No further relevant information available.

Bioaccumulative potential

No further relevant information available.

Other adverse effects

• Water hazard class 1: slightly hazardous for water.
• Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
• Must not reach sewage water or drainage ditch undiluted or unneutralised.

13. Disposal Considerations

General information

14. Transport Information

ADG label required

HAZCHEM

No further relevant information available.

UN Number

UN2927

Proper shipping name

2927 TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S, (SODIUM ACETATE TRIHYDRATE, ACETIC ACID, GLACIAL)

Transport hazard class

• Class: 6.1 Toxic substances.
• Label: 6.1, 8

Packing group

I

Environmental hazard

Not applicable.

Special precautions for users

• Warning: Toxic substances.
• Hazard identification number (Kemler code): 668
• EMS Number: F-A,S-B
• Segregation Groups: Acids
• Stowage Category: B
• Stowage Code: SW2 Clear of living quarters.

Additional information

• Limited quantities (LQ) 0
• Excepted quantities (EQ): Code: E5
• Maximum net quantity per inner packaging: 1mL
• Maximum net quantity per outer packaging: 300mL
• Transport category: 1
• Tunnel restriction code: C/E

15. Regulatory Information

Poisons Schedule Number

64-19-7 Acetic Acid Glacial S2, S5, S6

Other Information

• A Chemical Safety Assessment has not been carried out.
• Sara
• Section 355 (extremely hazardous substances):
• None of the ingredients is listed.
• Section 313 (Specific toxic chemical listings):
• None of the ingredients is listed.
• TSCA (Toxic Substances Control Act):
• 64-19-7 Acetic Acid Glacial ACTIVE
• 7732-18-5 Deionised Water, Reagent Grade A.C.S. ACTIVE
• Hazardous Air Pollutants: None of the ingredients is listed.
• Proposition 65
• Chemicals known to cause cancer: None of the ingredients is listed.
• Chemicals known to cause reproductive toxicity for females: None of the ingredients is listed.
• Chemicals known to cause reproductive toxicity for males: None of the ingredients is listed.
• Chemicals known to cause developmental toxicity: None of the ingredients is listed.
• Carcinogenic categories
• EPA (Environmental Protection Agency): None of the ingredients is listed.
• TLV (Threshold Limit Value): None of the ingredients is listed.
• NIOSH-Ca (National Institute for Occupational Safety and Health): None of the ingredients is listed.
• GHS label elements The product is classified and labeled according to the Globally Harmonized System (GHS).

16. Other Information

SDS preparation date

14 May 2026

Comments

• Abbreviations and acronyms:
• ADR: Accord relatif au transport international des marchandises dangereuses par route (European Agreement Concerning the International
• Carriage of Dangerous Goods by Road)
• IMDG: International Maritime Code for Dangerous Goods
• DOT: US Department of Transportation
• IATA: International Air Transport Association
• EINECS: European Inventory of Existing Commercial Chemical Substances
• ELINCS: European List of Notified Chemical Substances
• CAS: Chemical Abstracts Service (division of the American Chemical Society)
• NFPA: National Fire Protection Association (USA)
• HMIS: Hazardous Materials Identification System (USA)
• VOC: Volatile Organic Compounds (USA, EU)
• LC50: Lethal concentration, 50 percent
• LD50: Lethal dose, 50 percent
• PBT: Persistent, Bioaccumulative and Toxic
• vPvB: very Persistent and very Bioaccumulative
• NIOSH: National Institute for Occupational Safety
• OSHA: Occupational Safety Health
• TLV: Threshold Limit Value
• PEL: Permissible Exposure Limit
• REL: Recommended Exposure Limit
• Flammable liquids 3: Flammable liquids - Category 3
• Acute toxicity - oral 1: Acute toxicity - Category 1
• Skin corrosion 1B: Skin corrosion/irritation - Category 1B
• Eye damage 1: Serious eye damage/eye irritation - Category 1

References

EMS SDS "Acetate Buffer, 0.2M, pH 3.6-5.6" 29/01/2025 https://www.emsdiasum.com/docs/technical/msds/11480.pdf