Acetate Buffer, 0.2M, pH5.0

1. Identification

Product Identifiers

Product Name

Acetate Buffer, 0.2M, pH5.0

Other Names

Not available.

Product Number(s)

11482-50, EMS11482-50

CAS Number

Acetic acid: 64-19-7 Sodium acetate: 127-09-3

Recommended use of the chemical and restriction on use

Company Details

Emergency Contact Details

2. Hazards Identification

Classification of the substance or mixture

Label Elements

Signal Words

Danger

Hazard Statement(s)

• Hazard-determining components of labelling:
• Acetic Acid Glacial
• SODIUM ACETATE TRIHYDRATE
• Flammable liquid and vapour.
• Fatal if swallowed, in contact with skin or if inhaled.
• Causes severe skin burns and eye damage.

Precautionary Statement(s)

• Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• Ground / bond container and receiving equipment.
• Use explosion-proof [electrical/ventilating/lighting] equipment.
• Use non-sparking tools.
• Take action to prevent static discharge.
• Do not breathe dusts or mists.
• Do not get in eyes, on skin, or on clothing.
• Wash thoroughly after handling.
• Do not eat, drink or smoke when using this product.
• Use only outdoors or in a well-ventilated area.
• Wear protective gloves/protective clothing/eye protection/face protection/hearing protection.
• [In case of inadequate ventilation] wear respiratory protection.

Primary route(s) of entry

Human Health

Inhalation

remove person to fresh air and keep comfortable for breathing.

Ingestion

Immediately call a POISON CENTER/doctor. Rinse mouth. Do NOT induce vomiting.

Eyes

Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Skin

(or hair) Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash contaminated clothing before reuse.

Environment

3. Composition / Information on Ingredients

4. First Aid Measures

Ingestion

• Do not induce vomiting; call for medical help immediately.
• Drink plenty of water and provide fresh air. Call for a doctor immediately.

Inhalation

• Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if symptoms persist.
• In case of unconsciousness place patient stably in side position for transportation.

Skin Contact

Immediately wash with water and soap and rinse thoroughly.

Eye Contact

Rinse opened eye for several minutes under running water. Then consult a doctor.

Other Information

• Immediately remove any clothing soiled by the product.
• Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.
• In case of irregular breathing or respiratory arrest provide artificial respiration.

5. Firefighting Measures

Suitable extinguishing equipment

Fire

CO₂, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

HAZCHEM

For safety reasons unsuitable extinguishing agents: Water with full jet.

Special protective equipment and precautions for fire fighters

6. Accidental Release Measures

Personal precautions, protective equipment and emergency procedures

Wear protective equipment. Keep unprotected persons away.

Environmental precautions

• Dilute with plenty of water.
• Do not allow to enter sewers/ surface or ground water.

Methods and materials for containment and clean up

• Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
• Use neutralising agent.
• Dispose contaminated material as waste according to item 13.
• Ensure adequate ventilation.
• Do not flush with water or aqueous cleansing agents.
• Dispose contaminated material as waste according to section 13.
• Ensure adequate ventilation.
• · Protective Action Criteria for Chemicals
• · PAC-1:
• 64-19-7 Acetic Acid Glacial 5 ppm
• 6131-90-4 SODIUM ACETATE TRIHYDRATE 11 mg/m³
• · PAC-2:
• 64-19-7 Acetic Acid Glacial 35 ppm
• 6131-90-4 SODIUM ACETATE TRIHYDRATE 120 mg/m³
• · PAC-3:
• 64-19-7 Acetic Acid Glacial 250 ppm
• 6131-90-4 SODIUM ACETATE TRIHYDRATE 690 mg/m³

7. Handling and Storage

Precautions for safe handling

• Ensure good ventilation/exhaustion at the workplace.
• Open and handle receptacle with care.
• Prevent formation of aerosols.
• Information about protection against explosions and fires:
• Keep ignition sources away - Do not smoke.
• Protect from heat.
• Protect against electrostatic charges.
• Keep respiratory protective device available.

Conditions for safe storage

• Requirements to be met by storerooms and receptacles: No special requirements.
• Information about storage in one common storage facility: Not required.
• Further information about storage conditions:
• Keep receptacle tightly sealed.
• Protect from heat and direct sunlight.
• Specific end use(s) No further relevant information available.

8. Exposure Controls / Personal Protection

Exposure Standards

Engineering controls

• Keep away from foodstuffs, beverages and feed.
• Immediately remove all soiled and contaminated clothing.
• Wash hands before breaks and at the end of work.
• Avoid contact with the eyes.
• Avoid contact with the eyes and skin.

Personal protective equipment

Eye and face protection

Tightly sealed goggles.

Skin protection

• Protective gloves
• The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
• Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
• Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation.
• Material of gloves
• The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
• Penetration time of glove material
• The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

Body protection

Wear protective clothing.

Respiratory protection

In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air.

9. Physical and Chemical Properties

General information

Appearance

Clear liquid

Odour

Pungent

pH

5

Vapour Pressure

11.4hPa

Density

Not determined.

Boiling Point

118°C

Melting Point

Undetermined

Solubility

Fully miscible.

Specific Gravity of Density

Not available.

Flash Point

43 °C (109.4 °F)

Flammable (Explosive) Limits

• Lower: 4.0 Vol%
• Upper: 19.0 Vol%

Ignition Temperature

Product is not selfigniting.

Formula

Not available.

10. Stability and Reactivity

Reactivity

No further relevant information available.

Chemical stability

No decomposition if used according to specifications.

Possibility of hazardous reactions

No dangerous reactions known.

Conditions to avoid

No further relevant information available.

Incompatible materials

No further relevant information available.

11. Toxicological Information

Acute effects

• 64-19-7 Acetic Acid Glacial
• Oral LD50 3310 mg/kg (rat)
• Dermal LD50 1060 mg/kg (rabbit)

Eye contact

• Strong caustic effect.
• Strong irritant with the danger of severe eye injury.

Skin contact

Strong caustic effect on skin and mucous membranes.

Ingestion

Swallowing will lead to a strong caustic effect on mouth and throat and to the danger of perforation of oesophagus and stomach.

Inhalation

No sensitising effects known.

Toxicity and irritation

• The product shows the following dangers according to internally approved calculation methods for preparations:
• Corrosive
• Irritant
• Very toxic
• Danger through skin absorption.
• Swallowing will lead to a strong caustic effect on mouth and throat and to the danger of perforation of esophagus and stomach.
• Interactive effects No interactive effects between components are known.
• Carcinogenic categories
• IARC (International Agency for Research on Cancer): None of the ingredients is listed.
• NTP (National Toxicology Program): None of the ingredients is listed.
• OSHA-Ca (Occupational Safety Health Administration): None of the ingredients is listed.

12. Ecological Information

Ecotoxicity

No further relevant information available.

Persistence and degradability

No further relevant information available.

Bioaccumulative potential

No further relevant information available.

Other adverse effects

• Water hazard class 1: slightly hazardous for water.
• Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
• Must not reach sewage water or drainage ditch undiluted or unneutralised.

13. Disposal Considerations

General information

14. Transport Information

ADG label required

HAZCHEM

For safety reasons unsuitable extinguishing agents: Water with full jet.

UN Number

UN2927

Proper shipping name

• · DOT Toxic liquids, corrosive, organic, n.o.s. (SODIUM ACETATE TRIHYDRATE, Acetic acid, glacial)
• · ADR 2927 TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S. (SODIUM ACETATE TRIHYDRATE, ACETIC ACID, GLACIAL)
• · IMDG, IATA TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S. (SODIUM ACETATE TRIHYDRATE, ACETIC ACID, GLACIAL)

Transport hazard class

Class 6.1 Toxic substances · Label 6.1, 8

Packing group

I

Environmental hazard

Not applicable.

Special precautions for users

• Transport/Additional information:
• · DOT
• · Quantity limitations On passenger aircraft/rail: 0.5 L On cargo aircraft only: 2.5 L
• · ADR
• · Excepted quantities (EQ) Code: E5
• Maximum net quantity per inner packaging: 1 ml
• Maximum net quantity per outer packaging: 300 ml
• · IMDG
• · Limited quantities (LQ) 0
• · Excepted quantities (EQ) Code: E5
• Maximum net quantity per inner packaging: 1 ml
• Maximum net quantity per outer packaging: 300 ml
• · Special precautions for user Warning: Toxic substances
• · Poison inhalation hazard: Possible
• · Hazard identification number (Kemler code): 668
• · EMS Number: F-A,S-B
• · Segregation groups (SGG1) Acids
• · Stowage Category B
• · Stowage Code SW2 Clear of living quarters.

Additional information

• Limited quantities (LQ) 1L
• Excepted quantities (EQ) Code: E2
• Maximum net quantity per inner packaging: 30mL
• Maximum net quantity per outer packaging: 500mL
• Transport category: 2
• Tunnel restriction code: E

15. Regulatory Information

Poisons Schedule Number

64-19-7 Acetic Acid Glacial S2, S5, S6

Other Information

• Section 355 (extremely hazardous substances): None of the ingredients is listed.
• Section 313 (Specific toxic chemical listings): None of the ingredients is listed.
• TSCA (Toxic Substances Control Act):
• 64-19-7 Acetic Acid Glacial ACTIVE
• 7732-18-5 Deionized Water, Reagent Grade A.C.S. ACTIVE
• · Hazardous Air Pollutants: None of the ingredients is listed.
• Proposition 65
• · Chemicals known to cause cancer: None of the ingredients is listed.
• · Chemicals known to cause reproductive toxicity for females: None of the ingredients is listed.
• · Chemicals known to cause reproductive toxicity for males: None of the ingredients is listed.
• · Chemicals known to cause developmental toxicity: None of the ingredients is listed.
• Carcinogenic categories
• · EPA (Environmental Protection Agency): None of the ingredients is listed.
• · TLV (Threshold Limit Value): None of the ingredients is listed.
• · NIOSH-Ca (National Institute for Occupational Safety and Health): None of the ingredients is listed.

16. Other Information

SDS preparation date

14 September 2026

Comments

• Abbreviations and acronyms:
• ADR: Accord relatif au transport international des marchandises dangereuses par route (European Agreement Concerning the International
• Carriage of Dangerous Goods by Road)
• IMDG: International Maritime Code for Dangerous Goods
• DOT: US Department of Transportation
• IATA: International Air Transport Association
• EINECS: European Inventory of Existing Commercial Chemical Substances
• ELINCS: European List of Notified Chemical Substances
• CAS: Chemical Abstracts Service (division of the American Chemical Society)
• NFPA: National Fire Protection Association (USA)
• HMIS: Hazardous Materials Identification System (USA)
• VOC: Volatile Organic Compounds (USA, EU)
• LC50: Lethal concentration, 50 percent
• LD50: Lethal dose, 50 percent
• PBT: Persistent, Bioaccumulative and Toxic
• vPvB: very Persistent and very Bioaccumulative
• NIOSH: National Institute for Occupational Safety
• OSHA: Occupational Safety Health
• TLV: Threshold Limit Value
• PEL: Permissible Exposure Limit
• REL: Recommended Exposure Limit
• Flammable liquids 3: Flammable liquids – Category 3
• Acute toxicity - oral 1: Acute toxicity – Category 1
• Skin corrosion 1B: Skin corrosion/irritation – Category 1B
• Eye damage 1: Serious eye damage/eye irritation – Category 1

References

• Electrom Microscopy Science SDS "ACETATE BUFFER, 0.2M, pH 5.0." 01/03/2025
• https://www.emsdiasum.com/docs/technical/msds/11482-50.pdf